Over 10,000 people are employed by the nearly 1,700 business organizations in Rancho Mirage.

In 2016, Employment in Rancho Mirage was dominated by the Health and Medical service industry (35.4%) according to the California Employment Development Department. Retail sales (inflation adjusted) in the City of Rancho Mirage decreased by 31% between the years 2006-2010 reflecting the downturn in the economy but increased by 14.3% between 2011 and 2015.

Principal Employers – 2016
  Primary Description
Eisenhower Medical Center2,480  Hospital / Clinics
Agua Caliente Resort & Casino1,300  Casino
Omni Rancho Las Palmas Resort & Spa500  Hotel
Westin Mission Hills Resort & Spa470  Hotel
The Ritz Carlton Rancho Mirage & Spa397  Hotel
Hazelden Betty Ford Center269  Rehabilitation Center
indiGO Auto Group225  Auto Sales & Service225  Auto Sales & Service
Mission Hills Country Club211  Country Club
Cheesecake Factory180  Restaurant
Home Depot149  Home Improvement